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Check with a health care provider or pharmacist before utilizing other cough or cold medicines that may have dextromethorphan.
Codeine sulfate is definitely an opioid analgesic indicated with the reduction of mild to reasonably intense soreness in which using an opioid analgesic is appropriate.
Promethazine has adverse outcomes similar to These of other antihistamines and shares the harmful potentials with the phenothiazines; the standard safety measures of antihistamine and phenothiazine therapy ought to be observed. Some commercially out there formulations of promethazine hydrochloride comprise sulfites which could lead to allergic-variety reactions, which include anaphylaxis and everyday living-threatening or a lot less critical asthmatic episodes, in sure vulnerable men and women.
May possibly induce false-adverse or false-beneficial ends in pregnancy assessments that are determined by immunological reactions in between HCG and anti-HCG.
Excipients in commercially offered drug preparations might have clinically essential effects in some folks; consult distinct item labeling for particulars.
Codeine pharmacokinetics can be altered in sufferers with renal failure. Clearance may be reduced as well as the metabolites may possibly accumulate to Substantially better plasma degrees in sufferers with renal failure as compared with sufferers with regular renal function.
The protection and performance along with the pharmacokinetics of codeine sulfate in pediatric patients beneath the age of 18 have not been set up.
Adult doses of codeine greater than 60 mg fall short to offer commensurate reduction of agony and are connected with an appreciably amplified incidence of unwanted Negative effects.
Codeine can have an effect on your alertness or coordination. Do not push or do other get more info actions that have to have alertness or coordination till you know the way codeine impacts you.
Warning need to be utilized through concomitant usage of promethazine with medication possessing anticholinergic Houses.
An anticholinergic medicine, which incorporates antihistamines and medicines usually useful for overactive bladder, Parkinson’s disorder, or belly difficulties
The usual safeguards get more info needs to be observed and the opportunity of respiratory melancholy should be saved in mind.
Codeine is intended for oral use only. Abuse of codeine poses a danger of website overdose and death. The danger is improved with concurrent abuse of alcohol and various substances. Parenteral here drug abuse is commonly associated with transmission of infectious health conditions for instance hepatitis and HIV.
There's no specific antidote for phenothiazine get more info intoxication; nevertheless, anticholinergic antiparkinsonian medication might be beneficial in controlling extrapyramidal reactions associated with phenothiazine overdosage.